Mike Trout, Josh Lowe and Zach Neto hit home runs and the Los Angeles Angels beat the Houston Astros 6-2 on Friday night.
Javier Sanoja had three hits, Sandy Alcantara allowed one run over seven innings and the Miami Marlins opened the season with a 2-1 win over the Colorado Rockies.
England are held to a lacklustre draw by Uruguay at Wembley despite Ben White's goal on his international return.
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