eLife

Gβγ engages PLCβ3 at multiple sites to reorient and facilitate its activation

EM, biochemical, and cell-based assays to examine how Gβγ interacts with and potentiates PLCβ3. The authors present evidence for multiple Gβγ interaction surfaces and argue that Gβγ primarily enhances ...
eLife

The dominance of large-scale phase dynamics in human cortex, from delta to gamma

The phase of cortical activity, measured in the gray matter, is organized at multiple spatial scales, with the largest scales explaining most variance in phase at a given temporal frequency.

A2A Protocol Surpasses 150 Organizations, Lands in Major Cloud Platforms, and Sees Enterprise Production Use in First Year

Protocol project, hosted by the Linux Foundation, today announced major adoption milestones at its one-year mark, with more than 150 organizations supporting the standard, deep integration across ...
Virtualization Review

Running AI Natively on Windows 11 Using an eGPU

Tom Fenton reports running Ollama on a Windows 11 laptop with an older eGPU (NVIDIA Quadro P2200) connected via Thunderbolt dramatically outperforms both CPU-only native Windows and VM-based ...
British Journal of Ophthalmology

Publicly available multimodal large language models for ocular surface infections: benchmarking against corneal specialists in triage, diagnosis and treatment

Background/aims Ocular surface infections remain a major cause of visual loss worldwide, yet diagnosis often relies on slow ...