The heightened intrinsic activity resulting from loop confinement in enzymes arises synergistically from enthalpic and entropic contributions, which are contingent upon the extent of surface ...

Advanced microscopy techniques give scientists valuable clues for how to fight an enzyme that is leading to a rise in cases of antibiotic-resistant bacterial infections worldwide. Bacteria draw from ...

Specific glycans attached to the GnT-IVa and GnT-IVb can bind to the enzyme’s ligand-binding site, interfering with recognition and binding to the glycosylation proteins’ normal glycoprotein ...