Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function. However, the risk of arrhythmias following this procedure is ...

Myofibrillar myopathy type 6 (MFM6) is a rare genetic muscle disorder that leads to severe muscle weakness and a drastically shortened life expectancy due to a disruption in muscle protein regulation.

Findings show that impaired autophagy leads to muscle degeneration, inflammation, and mitochondrial defects, while ...

Fibroblasts are an essential component of the heart, as they play key roles in its structure, development and response to ...

Anatomically, cardiac rupture occurs at the intersection between injured and healthy cardiac tissue. This region is referred to as the borderzone. The conventional view is that increased mechanical ...

Researchers at the University Hospital Bonn have developed a humanized mouse model for myofibrillar myopathy type 6 (MFM6), revealing that impaired autophagy driven by a defective BAG3 protein leads ...

A series of recent physiology studies span from rare disease mechanisms to space-based biomedical advances. Findings include a new mouse model for myofibrillar myopathy type 6 that identifies ...

Myofibrillar myopathy type 6 (MFM6) is a rare genetic muscle disorder that leads to severe muscle weakness and a drastically ...

The results of a study by researchers at the International Centre for Genetic Engineering and Biotechnology (ICGEB) suggest ...

Study shows that cardiac spheroids, derived from human induced pluripotent stem cells, can be easily transported and injected into damaged areas of the heart to promote its regeneration and recovery ...